(R)-N-Boc-glutamic acid-1,5-dimethyl ester
(R)-N-Boc-glutamic acid-1,5-dimethyl ester
CAS: 59279-60-6
Molecular Formula: C12H21NO6
(R)-N-Boc-glutamic acid-1,5-dimethyl ester - Names and Identifiers
| Name | (R)-N-Boc-glutamic acid-1,5-dimethyl ester |
| Synonyms | Boc-Glu(OMe)-OMe BOC-GLU(OME)-OME BOC-L-GLU(OME)-OME BOC-L-GLUTAMIC ACID DIMETHYL ESTER (R)-N-Boc-glutamic acid-1,5-dimethyl ester dimethyl N-(tert-butoxycarbonyl)-L-glutamate Dimethyl N-(tert-Butoxycarbonyl)-L-glutamate 1,5-dimethyl (2S)-2-{[(tert-butoxy)carbonyl]amino}pentanedioate N-ALPHA-TERT-BUTYLOXYCARBONYL-L-GLUTAMIC ACID DI-METHYL DIESTER Dimethyl (2S)-2-[(2-methylpropan-2-yl)oxycarbonylamino]pentanedioate |
| CAS | 59279-60-6 |
| InChI | InChI=1/C12H21NO6/c1-12(2,3)19-11(16)13-8(10(15)18-5)6-7-9(14)17-4/h8H,6-7H2,1-5H3,(H,13,16)/t8-/m0/s1 |
(R)-N-Boc-glutamic acid-1,5-dimethyl ester - Physico-chemical Properties
| Molecular Formula | C12H21NO6 |
| Molar Mass | 275.3 |
| Density | 1.117±0.06 g/cm3(Predicted) |
| Melting Point | 43.0 to 47.0 °C |
| Boling Point | 370.9±32.0 °C(Predicted) |
| Flash Point | 178.1°C |
| Solubility | Chloroform (Slightly), DMSO (Slightly) |
| Vapor Presure | 1.07E-05mmHg at 25°C |
| Appearance | Liquid |
| Color | Colorless to pale yellow |
| pKa | 10.86±0.46(Predicted) |
| Storage Condition | Keep in dark place,Sealed in dry,Room Temperature |
| Refractive Index | 1.452 |
(R)-N-Boc-glutamic acid-1,5-dimethyl ester - Introduction
(R)-N-Boc-glutamic acid-1,5-dimethyl ester is an organic compound with a molecular formula of C12H20N2O6 and a molecular weight of 296.3g/mol. The following is an introduction to the nature, use, formulation and safety information of (R)-N-Boc-glutamic acid-1,5-dimer ester:
Nature:
-Appearance:(R)-N-Boc-glutamic acid-1,5-dimethyl ester is a white solid.
-Solubility: It has good solubility and high solubility in some organic solvents (such as dimethylformamide, dichloromethane, etc.).
-melting point:(R)-the melting point of N-Boc-glutamic acid-1,5-dimer ester is about 70-75°C.
Use:
- (R)-N-Boc-glutamic acid-1, 5-dimethylester is a commonly used amino acid compound. It is usually used as an intermediate in organic synthesis, and is widely used in drug synthesis and bioactive substances research.
Preparation Method:
- (R)-N-Boc-glutamic acid-1,5-dimethyl ester can be obtained by chemical modification of L-glutamic acid. A common preparation method is to first react L-glutamic acid with tert-butyl titanium dioxide (Boc2O) to give N-tert-butoxycarbonyl-L-glutamic acid, which is then reacted with methyl formate to give (R)-N-Boc-glutamic acid-1,5-dimethyl ester.
Safety Information:
- (R)-N-Boc-glutamic acid-1, 5-dimer ester is generally relatively safe under normal operating conditions. But as a chemical, still need to pay attention to the following matters:
-Avoid contact with skin and eyes to prevent inhalation and ingestion.
-Wear appropriate chemical protective gloves, goggles and protective clothing during use.
-Operate in a well-ventilated place to avoid dust and smoke.
-Storage should be sealed and kept away from fire and oxidizing agents.
-If you accidentally splash into your eyes or skin, rinse immediately with plenty of water and seek medical help.
-If taken by mistake or inhaled too much, seek medical attention immediately.
Nature:
-Appearance:(R)-N-Boc-glutamic acid-1,5-dimethyl ester is a white solid.
-Solubility: It has good solubility and high solubility in some organic solvents (such as dimethylformamide, dichloromethane, etc.).
-melting point:(R)-the melting point of N-Boc-glutamic acid-1,5-dimer ester is about 70-75°C.
Use:
- (R)-N-Boc-glutamic acid-1, 5-dimethylester is a commonly used amino acid compound. It is usually used as an intermediate in organic synthesis, and is widely used in drug synthesis and bioactive substances research.
Preparation Method:
- (R)-N-Boc-glutamic acid-1,5-dimethyl ester can be obtained by chemical modification of L-glutamic acid. A common preparation method is to first react L-glutamic acid with tert-butyl titanium dioxide (Boc2O) to give N-tert-butoxycarbonyl-L-glutamic acid, which is then reacted with methyl formate to give (R)-N-Boc-glutamic acid-1,5-dimethyl ester.
Safety Information:
- (R)-N-Boc-glutamic acid-1, 5-dimer ester is generally relatively safe under normal operating conditions. But as a chemical, still need to pay attention to the following matters:
-Avoid contact with skin and eyes to prevent inhalation and ingestion.
-Wear appropriate chemical protective gloves, goggles and protective clothing during use.
-Operate in a well-ventilated place to avoid dust and smoke.
-Storage should be sealed and kept away from fire and oxidizing agents.
-If you accidentally splash into your eyes or skin, rinse immediately with plenty of water and seek medical help.
-If taken by mistake or inhaled too much, seek medical attention immediately.
Last Update：2024-04-09 19:05:50
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